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A medium-chain fatty acid; has been found at high levels in coconut oil; induces the activation of NF-κB and the expression of COX-2, iNOS, and IL-1α in RAW 264.7 cells at 25 µM
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Isovalerylcarnitine chloride is the chloride salt of isovalerylcarnitine, a metabolic product of L-leucine that acts as a potent activator of Ca2+-dependent protease (calpain). Supplied as a research-grade analytical standard, it is intended for in vitro and analytical use and is accompanied by a datasheet, COA, and SDS.
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Octanoic acid (CAS 124-07-2) also referred to as caprylic acid is a saturated fatty acid comprising an eight-carbon aliphatic chain Naturally present in sources such as coconut oil and breast milk octanoic acid is known for its amphipathic properties and moderate water solubility In research octanoic acid has been utilized to study lipid metabolism cellular energy production and the modulation of membrane structure due to its role as a medium-chain fatty acid It also exhibits antimicrobial activity attributed to its capacity to disrupt microbial cell membranes Octanoic acid is widely applied in investigations involving metabolic disorders mitochondrial function and microbiological models
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An analog of 1,24-dihydroxy vitamin D3 which, when used in a 4 μg/g ointment, suppresses psoriasis; inhibits the growth of both normal and psoriatic human keratinocytes (IC50 ~ 10 nM) via the vitamin D receptor; suppresses the production of RANTES and IL-8 by human dermal fibroblasts
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Larixyl acetate is a diterpenoid research chemical used as an analytical standard and a tool compound in pharmacology studies. It acts as a potent, selective TRPC6 inhibitor with reported hTRPC6 IC50 = 0.58 μM and activity against hTRPC3. Supplied as a solid or as a 10 mM solution in DMSO, it is intended for research use only and requires low-temperature storage to preserve stability.